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Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

null

《医学前沿（英文）》 2015年 第9卷 第1期   页码 72-76 doi: 10.1007/s11684-014-0347-x

摘要：

Periodontitis is an inflammatory disease of the periodontium. Any imbalance between the matrix metalloproteinases (MMPs) secreted by neutrophils and tissue inhibitors initiates the destruction of collagen in gum tissue, leading to chronic periodontitis. This study aimed to correlate salivary levels of MMP-8 and periodontal parameters of chronic periodontitis to establish MMP-8 as a noninvasive marker for the early diagnosis of chronic periodontitis. The study involved 40 subjects visiting the periodontic OPD of Dr. Ziauddin Ahmad Dental College and Hospital, located in Aligarh, U.P., India, from 2011 to 2012. The subjects were divided into two groups: group I consisted of 20 periodontally healthy subjects (controls) while group II consisted of 20 patients with chronic periodontitis. Chronic periodontitis was assessed on the basis of several periodontal parameters, including pocket probing depth (PPD), clinical attachment level (CAL), gingival index (GI), and plaque index (PI). Around 3 ml of unstimulated and whole expectorated saliva was collected for MMP-8 estimation by ELISA using Quantikine human total MMP-8 immunoassay kits. Data were analyzed using STATISTICA (Windows version 6) software. Salivary MMP-8 levels of groups I and II were 190.91±143.89 ng/ml and 348.26±202.1 ng/ml, respectively. The MMP-8 levels and periodontal status (PPD, CAL, GI, and PI) of groups I and II showed positive and significant correlations (for PPD, r = 0.63, P<0.001; for CAL, r = 0.54, P<0.001; for GI, r = 0.49, P<0.001; and for PI, r = 0.63, P<0.001). The results of this study demonstrate elevated concentrations of MMP-8 in individuals with chronic periodontitis.

关键词： matrix metalloproteinase-8     chronic periodontitis     pocket probing depth     clinical attachment level     gingival index     plaque index    

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Treatment of gingival hyperplasia induced by cyclosporine A

MA Jingzhi, LI Ming, CAO Yingguang

《医学前沿（英文）》 2008年 第2卷 第3期   页码 290-294 doi: 10.1007/s11684-008-0055-5

摘要： The clinical therapy for cyclosporine A (CsA)-induced gingival hyperplasia (GH) and the pathological changes in hyperplastic gingival tissues were investigated. Nine cases of CsA-induced GH after renal transplantation were subjected to periodontal non-surgical treatment and surgical treatment and were followed up. Gingival index (GI), dental plaque index (PLI) and GH degree (GHD) at different time points were measured. Under light and electron microscopy, the pathological changes in hyperplastic gingival tissues were observed. The CsA concentrations in gingival tissues and blood were determined by using fluorescence polarization immunoassay with TDFL monoclonal antibody. The results showed that GI, PLI and GHD in patients with GH declined after periodontal treatment. Two patients suffered from different degrees of GH during the 6 months to 54 months post-transplantation. Under transmission electron microscopy, fibroblasts in the hyperplastic gingival tissues were enlarged, cytoplasmic rough endoplasmic reticula were abundant and expanded slightly, and a few fibroblasts with early apoptotic changes were seen. The concentrations of CsA in hyperplastic gingival tissues were from 351.00 to 1345.47 ng/mL, which were significantly higher than in the blood of the same patients taken at the same time points. It was concluded that GI and PLI declined after periodontal treatment in combination with surgical treatment in patients taking CsA for a long time, but in some patients, GH recurred. The fact that the concentration of CsA in hyperplastic gingival tissues is higher than in blood awaits further studies.

关键词： post-transplantation     Gingival     cytoplasmic     CsA-induced     further    

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Research on port ecological suitability evaluation index system and evaluation model

Yaofeng XIE,Xia LV,Ru LIU,Liuyan MAO,Xiaoxi LIU

《结构与土木工程前沿（英文）》 2015年 第9卷 第1期   页码 65-70 doi: 10.1007/s11709-014-0258-6

摘要： Along with the rapid development of port building, the negative impacts of port’s construction and operation on the coastline ecosystem are also increasingly strong. Therefore, it’s urgent to establish a scientific and complete system of port ecological suitability evaluation. This paper pointed out the characteristics of port ecological effects and the principles of selecting evaluation index, and used the “pressure-state-response (PSR)” model to analysis the various pressures on the environment caused by port construction and operation, and the system’s response. On this basis, we constructed the port ecological suitability evaluation index. This model used the combination of qualitative and quantitative analytic hierarchy process, to meet the multi-level, multi-objective characteristics of evaluation index system. The evaluation index system and evaluation model can be used to analysis the ecological suitability of port projects comprehensively and have some guiding significance to the port ecological suitability evaluation.

关键词： port     ecological suitability     press-state-response (PSR) model     evaluation index system    

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A total torque index for dynamic performance evaluation of a radial symmetric six-legged robot

Kejia LI, Xilun DING, Marco CECCARELL

《机械工程前沿（英文）》 2012年 第7卷 第2期   页码 219-230 doi: 10.1007/s11465-012-0320-9

摘要：

This article focuses on the dynamic index and performance of a radial symmetric six-legged robot. At first the structure of the robot is described in brief and its inverse kinematics is presented. Then the dynamic model is formulated as based on the Lagrange equations. A novel index of total torque is proposed by considering the posture of the supporting legs. The new index can be used to optimize the leg’s structure and operation for consuming minimum power and avoiding unstable postures of the robot. A characterization of the proposed six-legged robot is obtained by a parametric analysis of robot performance through simulation using the presented dynamic model. Main influences are outlined as well as the usefulness of the proposed performance index.

关键词： six-legged robots     dynamic modeling     performance index    

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determination of tobramycin by reversed-phase ion-pair high performance liquid chromatography with a refractive index

Liang ZHU, Jingkang WANG

《化学科学与工程前沿（英文）》 2013年 第7卷 第3期   页码 322-328 doi: 10.1007/s11705-013-1348-z

摘要： A simple and direct method without a derivation step for routine analysis of tobramycin has been developed. This method used reversed-phase ion-pair high performance liquid chromatography (HPLC) with a refractive index (RI) detector and a C18 column which is stable at pH above 1.00. The presence of 4.50 mg·mL trifluoroacetic acid (TFA) in the mobile phase improved the protonation of tobramycin and the formation of ion-pairs, and thus reduced its hydrophility. This unique separation–detection combination showed good linearity with correlation coefficients 0.9996 in the concentration range of 0.25–2.50 mg·mL . The quantitation limit and detection limit were determined to be 0.23 mg·mL and 0.071 mg·mL , respectively. Tobramycin was recovered in 98.00%, 98.84% and 99.64% for tobramycin solutions at concentrations of 2.25 mg·mL , 1.50 mg·mL and 0.75 mg·mL , respectively. The relative standard deviations for six spiked samples ranged from 0.20% to 2.40%, indicating a good reproducibility of this method.

关键词： tobramycin     aminoglycoside     refractive index detector     high-performance liquid chromatography     ion-pairing    

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Isolating higher yielding and more stable rice genotypes in stress environments: fine-tuning a selection method using production and resilience score indices

《农业科学与工程前沿（英文）》 doi: 10.15302/J-FASE-2023521

摘要：

● Score index methods readily discriminate genotypes adapted to a target environment.

关键词： Aerobic rice     breeding selection     drought resilience     production capacity index     resilience capacity index     stress score index     upland    

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SUSTAINABLE NITROGEN MANAGEMENT INDEX: DEFINITION, GLOBAL ASSESSMENT AND POTENTIAL IMPROVEMENTS

《农业科学与工程前沿（英文）》 2022年 第9卷 第3期   页码 356-365 doi: 10.15302/J-FASE-2022458

摘要：

● A composite N management index is proposed to measure agriculture sustainability.

关键词： global assessment     indicator     nitrogen management     sustainable agriculture     sustainable development goals    

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A novel power system reconfiguration for a distribution system with minimum load balancing index using

K. Sathish KUMAR, T. JAYABARATHI

《能源前沿（英文）》 2012年 第6卷 第3期   页码 260-265 doi: 10.1007/s11708-012-0196-8

摘要： In this paper, the objective of minimum load balancing index (LBI) for the 16-bus distribution system is achieved using bacterial foraging optimization algorithm (BFOA). The feeder reconfiguration problem is formulated as a non-linear optimization problem and the optimal solution is obtained using BFOA. With the proposed reconfiguration method, the radial structure of the distribution system is retained and the burden on the optimization technique is reduced. Test results are presented for the 16-bus sample network, the proposed reconfiguration method has effectively decreased the LBI, and the BFOA technique is efficient in searching for the optimal solution.

关键词： bacterial foraging optimization algorithm (BFOA)     distribution system     network reconfiguration     load balancing index (LBI)     radial network    

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The Building of Papermaking Enterprise’s Recycling Economy Evaluation Index System Based on Value Flow

Zhi-fang Zhou,Jing Ou,Sha-sha Wang,Xiao-hong Chen

《工程管理前沿（英文）》 2016年 第3卷 第1期   页码 9-17 doi: 10.15302/J-FEM-2016009

摘要： At present, the research on circular economy has made a lot of substantive results both at home and abroad. But for the papermaking enterprise, which is the representative of the light industry, few studies have analyzed the evaluation index system of circular economy. Since the current material flow analyses have limitations that the researchers cannot calculate materials with different units. The authors take advantage of the intrinsic correlation between the basic principle of value flow analysis and circular economy, and then analyze the dynamic changes of material flow and value flow through enterprises internal production process. Considering the resource output, the authors set up the layered structure of the evaluation index system, and then preliminarily determine the index form. Next, the authors use the frequency statistics analysis method to adjust indicators, forming a preliminary index system. After that, the principal component analysis and independent analysis are applied for screening. Finally, the authors build a circular economy evaluation index system for papermaking enterprise to provide scientific guidance for the process of circular economy.

关键词： circular economy     the papermaking enterprise     material flow analysis     value flow analysis     evaluation index system    

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Can the Shanghai LNG Price Index indicate Chinese market?

Yeli ZENG, Cong DONG, Mikael HÖÖK, Jinhua SUN, Danyang SHI

《能源前沿（英文）》 2020年 第14卷 第4期   页码 726-739 doi: 10.1007/s11708-020-0701-4

摘要： China became the world’s second largest liquefied natural gas (LNG) importer in 2018 but has faced extremely high import costs due to a lack of bargaining power. Assessments of the Shanghai LNG Price Index, first released in 2015, are vital for improving the understanding of these cost dynamics. This paper, using the LNG price index data from the Shanghai Petroleum and Gas Exchange (SHPGX) coupled with domestic and international LNG prices from July 1, 2015 to December 31, 2018, estimates several econometric models to evaluate the long-term and short-term equilibriums of the Shanghai LNG Price Index, the responses to market information shocks and the leading or lagging relationships with LNG and alternative energy prices from other agencies. The results show that the LNG price index of the SHPGX has already exhibited a long-term equilibrium and short-term adjustment mechanisms to reflect the average price level and market movements, but the market information transparency and price discovery efficiency of the index are still inadequate. China’s LNG market is still relatively independent of other natural gas markets, and marketization reforms are under way in China. The influence of the SHPGX LNG price index on the trading decisions of market participants is expected to improve with further development of China’s LNG reforms, the formation of a natural gas entry-exit system, and the increasing liquidity of the hub.

关键词： liquefied natural gas     price index     Shanghai Petroleum and Gas Exchange     price discovery     market reforms    

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“制造强国”评价指标体系优化与测评研究

赵蔷,吴进军,夏鹏,王迪,刘丹,刘云,董晗

《中国工程科学》 2017年 第19卷 第3期   页码 13-19 doi: 10.15302/J-SSCAE-2017.03.003

摘要：

本文围绕制造强国指标体系数据源、计算方式、指标归类等方面进行了完善优化研究，持续开展了年度指数测评工作及指数背后制造业发展态势的深入剖析。同时对2016年制造强国综合指数进行了预测算，总结了近五年的发展趋势，为制造强国发展进程提供了有益的参考。

关键词： 指标体系     完善优化     指数测评     差距及瓶颈分析    

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制造质量强国指标体系研究

郑立伟,张纲,蒋家东,王赟松

《中国工程科学》 2015年 第17卷 第7期   页码 76-75

摘要：

本文构建了制造质量强国指标体系，分为质量安全、质量发展和质量基础三个维度，建立了11个评价指标。通过实证分析将我国制造业产品质量与部分国家进行了比较，并分析了我国制造业质量水平变化的趋势。结论表明：我国制造业质量经历了一个稳步提升的过程，2008年金融危机后提升幅度明显下降；与新兴制造国家相比，我国产品质量表现出一定优势；与发达国家相比，仍存在安全、性能差距，影响了我国制造业的出口贸易。

关键词： 制造强国     质量评价     指标体系    

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Pavement sustainability index for highway infrastructures: A case study of Maryland

Stella O. OBAZEE-IGBINEDION, Oludare OWOLABI

《结构与土木工程前沿（英文）》 2018年 第12卷 第2期   页码 192-200 doi: 10.1007/s11709-017-0413-y

摘要： Pavement deterioration creates conditions that undermine their performances, which gives rise to the need for maintenance and rehabilitation. This paper develops a mathematical multi-linear regression analysis (MLRA) model to determine a pavement sustainability index ( ) as dependent variable for flexible pavements in Maryland. Four categories of pavement performance evaluation indicators are subdivided into seven pavement condition indices and analyzed as independent variables for each section of pavement. Data are collected from five different roadways using field evaluations and existing database. Results indicate that coefficient of determination ( ) is correlated and significant, = 0.959. Of the seven independent variables, present serviceability index ( ) is the most significant with a coefficient value of 0.032, present serviceability rating ( ) coefficient value= 0.028, and international roughness index ( ) coefficient value= ?0.001. Increasing each unit value of coefficients for and would increase the value of ; thereby providing a more sustainable pavement infrastructure; which explains the significance of the model and why will most likely impact environmental, economic and social values.

关键词： pavement indices     sustainability     pavement performance     flexible pavements    

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高层建筑火灾风险评估的指标体系设计

刘爱华,施式亮,吴超

《中国工程科学》 2006年 第8卷 第9期   页码 90-94

摘要：

针对高层建筑火灾危险的特点， 通过对火灾场景的设定，从消防对策的角度对火灾进行了阶段划分，并针对每个阶段运用了事故树和事件树的方法进行了事故分析，找出了影响火灾发展和蔓延的相关因素，建立了多层次的高层建筑火灾危险评价的指标体系。该指标体系能为建筑物安全管理提供科学依据，也能为高层建筑火灾风险评估奠定基础。

关键词： 高层建筑火灾     指标体系     火灾场景     火灾阶段划分    

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水污染防治生物处理技术验证评估指标研究

许春莲,张伟,宋乾武,黄海明,田艳丽,陈栋

《中国工程科学》 2013年 第15卷 第3期   页码 44-48

摘要：

建立科学的验证评估指标体系是开展环境技术验证评估的前提条件。立足于水污染防治生物处理技术，以公正、科学、保护知识产权等为原则，在总结国外验证评估指标体系、验证评估方法的基础上，结合我国的国情开展了水污染防治技术验证评估指标的设计。验证指标共分参考指标、测试指标、评价指标3个部分，按特性又划分为通用指标和特征指标两类。

关键词： 生物处理技术     验证评估     指标    

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标题 作者 时间 类型 操作

Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

null

期刊论文

Treatment of gingival hyperplasia induced by cyclosporine A

MA Jingzhi, LI Ming, CAO Yingguang

期刊论文

Research on port ecological suitability evaluation index system and evaluation model

Yaofeng XIE,Xia LV,Ru LIU,Liuyan MAO,Xiaoxi LIU

期刊论文

A total torque index for dynamic performance evaluation of a radial symmetric six-legged robot

Kejia LI, Xilun DING, Marco CECCARELL

期刊论文

determination of tobramycin by reversed-phase ion-pair high performance liquid chromatography with a refractive index

Liang ZHU, Jingkang WANG

期刊论文

Isolating higher yielding and more stable rice genotypes in stress environments: fine-tuning a selection method using production and resilience score indices

期刊论文

SUSTAINABLE NITROGEN MANAGEMENT INDEX: DEFINITION, GLOBAL ASSESSMENT AND POTENTIAL IMPROVEMENTS

期刊论文

A novel power system reconfiguration for a distribution system with minimum load balancing index using

K. Sathish KUMAR, T. JAYABARATHI

期刊论文

The Building of Papermaking Enterprise’s Recycling Economy Evaluation Index System Based on Value Flow

Zhi-fang Zhou,Jing Ou,Sha-sha Wang,Xiao-hong Chen

期刊论文

Can the Shanghai LNG Price Index indicate Chinese market?

Yeli ZENG, Cong DONG, Mikael HÖÖK, Jinhua SUN, Danyang SHI

期刊论文

“制造强国”评价指标体系优化与测评研究

赵蔷,吴进军,夏鹏,王迪,刘丹,刘云,董晗

期刊论文

制造质量强国指标体系研究

郑立伟,张纲,蒋家东,王赟松

期刊论文

Pavement sustainability index for highway infrastructures: A case study of Maryland

Stella O. OBAZEE-IGBINEDION, Oludare OWOLABI

期刊论文

高层建筑火灾风险评估的指标体系设计

刘爱华,施式亮,吴超

期刊论文

水污染防治生物处理技术验证评估指标研究

许春莲,张伟,宋乾武,黄海明,田艳丽,陈栋

期刊论文